Adenomatoid odontogenictumor occupying maxillary sinus: a case report withhistopathologic study and review of the literature

Kazuhito HORINO^1）,MakotoOHNISHI^2）,MasashiMURATA ^3）4）,TakashiSAKU^3）
1）Departmant of Dentistry and Oral Surgery, Niigata prefecturalYoshida Hospital(Chief: Dr.Kazuhito HORINO)
2）Departmant of Dentistry and Oral Surgery, Nagaoka Red CrossHospital(Chief: Dr.Makoto OHNISHI)
3）Department of Oral Pathology, Niigata University School ofDentistry(Chief: Prof.Takashi SAKU)
4）Department of Periodontology, Niigata University School ofDentistry(Chief: Prof.Kohji HARA)

Abstract
　We report a case of adenomatoid odontogenic tumor in themaxillary bone. The patient was an 11-year-old girl whocomplained of cheek swelling. X-ray examination revealed that thetumor involved an impacted canine in its cystic lesion andoccupied most of the space of left maxillary sinus, and containedmicrocalcifications. The lesion was extirpated under generalanesthesia and examined histopathologically, to be diagnosed asadenomatoid odontogenic tumor. On histologic examination, itshowed characteristic duct-like structures and whorled or rosettemasses of tumor cells. The rim and amorphous contents ofduct-like structures and eosinophilic droplets among solid nestsof columnar cells were much of eosinophilic and argyrophilicmaterials. In immunohistochemical staining, they also showedstrong immunoreactivity for heparan sulfate proteoglycan,laminin, and collagen type IV.

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